COMLEX-USA: Osteopathic Physician MCQs and Practice Test | Updated March, 2026

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Osteopathic Physician Practice Test

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MCQs

NBOME COMLEX-USA : Osteopathic Physician exam Questions, MCQs and Practice Test

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Latest 2026 MCQs of NBOME Osteopathic Physician
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COMLEX-USA MCQs : Download 100% Free COMLEX-USA exam Questions (PDF and VCE)

Exam Number : COMLEX-USA
Exam Name : Osteopathic Physician
Vendor Name : NBOME
Update : Click Here to Check Latest Update
Total MCQs : Check Questions

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COMLEX-USA exam Format | COMLEX-USA Course Contents | COMLEX-USA Course Outline | COMLEX-USA exam Syllabus | COMLEX-USA exam Objectives


Test Detail:
The COMLEX-USA (Comprehensive Osteopathic Medical Licensing exam of the United States) is a series of three exams designed to assess the knowledge and clinical skills of osteopathic physicians. The COMLEX-USA exam is administered by the National Board of Osteopathic Medical Examiners (NBOME). The following description provides an overview of the COMLEX-USA exam.

Course Outline:
To prepare for the COMLEX-USA exam- candidates typically complete a comprehensive medical education program- including preclinical and clinical coursework- as well as clinical rotations in various specialties. The coursework covers a wide range of medical topics- including anatomy- physiology- biochemistry- pharmacology- pathology- and clinical medicine. The curriculum is designed to provide students with a strong foundation in medical knowledge and clinical skills necessary for osteopathic practice.

Exam Objectives:
The COMLEX-USA exam aims to assess the candidate's proficiency in various domains of osteopathic medical practice. The exam objectives include the following:

1. Osteopathic Principles and Practice (OPP):
- Knowledge and application of osteopathic principles
- Osteopathic manipulative treatment (OMT) skills and techniques
- Understanding the integration of osteopathic principles in patient care

2. Biomedical Sciences:
- Knowledge and understanding of basic medical sciences- including anatomy- physiology- biochemistry- pharmacology- microbiology- and pathology
- Integration of basic science principles in clinical decision-making

3. Clinical Skills and Patient Care:
- Clinical exam and diagnostic skills
- Patient management and treatment planning
- Effective communication and interpersonal skills with patients and healthcare team members

4. Clinical Medicine:
- Diagnosis and management of common medical conditions
- Understanding of various medical specialties and subspecialties
- Application of evidence-based medicine in clinical practice

Exam Syllabus:
The COMLEX-USA exam syllabus covers a broad range of medical knowledge and clinical skills. The syllabus includes courses from various medical disciplines- including:

- Anatomy and embryology
- Physiology and pathophysiology
- Biochemistry and molecular biology
- Pharmacology and therapeutics
- Microbiology and immunology
- Pathology and laboratory medicine
- Osteopathic principles and practice
- Clinical medicine and differential diagnosis
- Osteopathic manipulative treatment (OMT)

The COMLEX-USA exam is divided into three levels: Level 1- Level 2-Cognitive Evaluation (CE)- and Level 2-Performance Evaluation (PE). Each level assesses different aspects of medical knowledge and clinical skills. The exam format includes multiple-choice questions- clinical case simulations- and hands-on practical exams for OMT skills.



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